Leave a request
Bronchial asthma is commonly called as asthma, is a chronic disease of respiratory tract which is associated with inflammation of the airways of the lungs that causes coughing, wheezing, shortness of breath, and chest tightness.
Since, asthma is caused by inflamed airways. Swelling and muscle tightness can cause the airways to become narrow, thus limiting the supply of air to the lungs. This makes it hard for the person to breathe which eventually leads to an asthma attack.
Patients were selected based on presence of classical symptoms these divided into two group gives them Shrishadyavaleh with Virechana at dose dependent manner.
As, this is concluded that the effect of Shrishadyavaleh With Virechana on asthma is useful to cure in elevation manner.
Bronchial asthma; Chronic disease; Respiratory tract; Lungs; Virechana
Asthma is related with mast cells, eosinophils, and T lymphocytes . The most important, Mast cells (allergycausing cells that release chemicals like histamine). But, Histamine nothing but substance that causes nasal stuffiness and dripping in a cold or hay fever, constriction of airways in asthma, and itchy areas in a skin allergy . Eosinophils (type of white blood cell), which is associated with allergic disease . T lymphocytes (white blood cells), which is associated with allergy and inflammation . According to the World Health Organization, there are around 15-20 million bronchial asthma patients in India .
Tamaka Swasa is mentioned as one of the variety among five types of Swasa. Tamaka Swasa is a Swatantra Vyadhi having its own etiology, pathology and Management. It is mentioned as Yaapya Vyadhi. Bronchial asthma mentioned in Modern Medicine closely resembles with Tamaka Swasa .
Bronchial Asthma is a major chronic airway disorder. It is a serious public health problem in countries throughout the world. Asthma effects peoples of all age and can be severe, sometimes fatal over two million people worldwide are suffering from Asthma, the prevalence is also increasing among children very fast .
As with all chronic diseases, rising prevalence is only part of the concern related to children. Mortality due to asthma one in last decade and has not changed in recent years. Morbidity due to exacerbations and persistent symptoms present as a huge burden to individuals the community for e.g. in the United States, over two million school days were lost in one year by children asthma. The consequent lost productivity of their parents was almost 1 billion, many chronic diseases asthma often appears early in childhood . The life-long consequences inadequately treated asthma can besubstantial. A major burden of asthma falls on the developing world especially in terms disability adjusted life years. The extent of Burden of asthma is related to it. Although patients with severe asthma are in number than those with milder asthma with inadequately controlled severe asthma expenditure in health care cost especially hospitalization.
Asthma may be defined based on pathology of functional consequences as Asthma, is a health inflammatory disorder of the airways in cells plays a role mast T-lymphocytes . In susceptible his inflammation causes recurrent episodes of wheezing, breathlessness, chest tightness and cough particularly at night, or in the early morning. These symptoms are usually associated with wide spread but variable air flow limitation that is at least party reversible either spontaneously or with treatment. The inflammation also causes associated increase airway responsiveness to a variety of stimuli .
So, its emerging need of innovative way to treat Asthma because of increasing incidence.
Place of study: Multicentric
Patients were selected based on presence of classical symptoms of Tamaka Swasa Patients were than subjected to the detailed clinical history and physical, examination based on specially prepared Research Proforma (Questioner). Total 30 patients were registered for this study. All the patients were randomly divided into two groups as follows. We took writer consent form from each patient. Those who are not ready to give consent form, that patient excluded from the study.
Virechana-Avaleha group (A)
In this group, 12 patients were given Shirishadyavaleha in dose of 10 g bid for duration of 1 month after performing Virechana Karma. Out off these 10 have completed the course.
Avaleha group (B)
In this group 18 patient were given Shirishadyavaleha in dose of 10 g bid for 1 month out of these 13 have completed the course. The tone of this study is both conceptual and clinical. Clinical study includes observations and results obtained in present study followed by discussion and conclusion which was observed in present study.
To assess the efficacy of remedy Shrishadyavaleha, scientific clinical study has been designed. This clinical trial carefully and ethically designed experiment with an aim to answer precisely framed questions. It is a mean to evaluate the efficacy and tolerability of a treatment Human beings. Details of clinical study are as follows.
Constituents of drugs
The drug clinical trial was Shirishadyavaleha. Shirisha, Vasa, Bharangi, Kantakari, Pippali, Hritaki in equal parts. Arka Pushpa and Trijata was used as Prakshepa dravya (1/20th part) Avaleha preparation in the form of Gudavaleha was prepared with Purana Guda.
Criteria of assessment
Improvement in Rogabala along with Deha, Agni and Chetasa bala was considered for assessment in this study an effort has been made to follow the guidelines laid down by Aacharya Charka for assessment of Results. Total 100 score has been divided in following. Rogabala, Dehabala, Agnibala and Sotvabala.
Roga-Balal (60 score)
Roga Bala has been given 60 score out of 100 for of degree of disease activity and symptoms. This score has been further subdivided as following.
Swasa Kashtata (25 score): It has been further divided as Dyspnoea: 5 score, Duration: 4 score, Intensity: 4 score, Presence of pranavaha Sroto Dusti Lakshana: 4 score, Frequency: 4 score, Asino Labhate Saukhyam: 4 score.
KAASA (10 score): It has been further divided as Kaasa: 4 score, Kaasatah Sanniruddhyate: 2 score, Kaphanishtivanama: 2 score, Shleshma Vimokshante Saukhyama: 2 score.
Associated symptoms (25 score): It has been further divided as Peenasa: 2 score, Parshvashula: 2 score, Kanthodhvansana: 2 score, Ushnabhinandati: 2 score. Trita/ Vishushkasyata: 2 score, Wheeze: 5 score, A.E.C.: 5 score, Peer: 5 score.
Agnibala (20 score)
It has been further divided as Jaranashakti: 6 score, Abhyavaharanashakti: 6 score, Ruchi Hi Aaharakale: 4 score, Vata Mutra Purisha Retasam Mukti: 4 score.
Dehabala (10 score)
It has been further divided as Balavriddhi: 4 score, Swara V ama Yoga: 4 score, Sharira Upachaya: 2 score.
Satvabala (10 score)
It has been further divided as Nidra Labhoyathakalam: 4 score, Sukhena cha pratibodhanam: 2 score, Vaikarikanam Cha Swapnanam Adarshanam: 2 score, Mano Buddhi Indriya Avyappatti: 2 score.
Effect of therapy
For the assessment of results, an effort has been made to use the classical tools of assessment as described by Charka. As classical references, for the assessment of results, four criteria's i.e. Roga Bala, Deha bala, Agni Bala, Chetasa Bala were adopted.
Leave a request